高铁血红蛋白
Multi tool use
The structure of the enzyme that converts methemoglobin to hemoglobin
[1]
高铁血红蛋白[2]（也稱變性血紅素[3]，英语：Methemoglobin或英语：Methaemoglobin[註 1]）是氧携带金属蛋白血红蛋白的一种形式，这种血红蛋白中血红素基团裡的铁离子呈正三价状态（高铁状态，Fe3+），并不是正常血红蛋白中的正二价状态。不像氧合血红蛋白，高铁血红蛋白无法释放被结合上去的氧气。这种蛋白在血液中呈现浅蓝-棕色。NADH依赖型酶高铁血红蛋白还原酶负责将高铁血红蛋白变回原来正常的血红蛋白。
参考文献
^ Bando, S.; Takano, T.; Yubisui, T.; Shirabe, K.; Takeshita, M.; Nakagawa, A. Structure of human erythrocyte NADH-cytochromeb5reductase. Acta Crystallographica Section D. 2004, 60 (11): 1929–1934. PMID 15502298. doi:10.1107/S0907444904020645.
^ ［学科］ 生物化学与分子生物学 —> 氨基酸、多肽与蛋白质. 全国科学技术名词审定委员会 （中文（简体））. [永久失效連結]
^ methemoglobin - 變性血紅素. 國家教育研究院雙語詞彙、學術名詞暨辭書資訊網. 國家教育研究院. [2018-05-21] （中文（台灣））.
外部链接
MeSH（醫學主題詞）上面的Methemoglobin（美式英语）
- MetHb Formation
- The Blue people of Troublesome Creek
蛋白质：血红素蛋白
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| 珠蛋白 |
血红蛋白 |
亚基 |
16号染色体上的
α亚基等:
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11號染色體上的
β亚基等:
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四聚体 |
发育阶段： HbA (α2β2) · HbA2 (α2δ2) · HbF/Fetal (α2γ2) · HbE Gower 1 (ζ2ε2) · HbE Gower 2 (α2ε2)
病理状态： HbH (β4) · HbS (α2βS2) · HbC (α2βC2)
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组成 |
碳氧血红蛋白 · 氨甲酰血红蛋白 · 氧合血红蛋白/去氧血红蛋白 · 硫血红蛋白
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人类其他 |
糖化血红蛋白 · 高铁血红蛋白
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非人类 |
血绿蛋白 · 无脊椎动物血红蛋白
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其他 |
人类： 肌红蛋白（正铁肌红蛋白） · 神经珠蛋白 · 细胞球蛋白
植物： 豆血红蛋白
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| 其他 |
细胞色素（细胞色素b、细胞色素P450） · 血蓝蛋白 · 假正铁血红蛋白
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骨髓來源細胞索引
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| 描述 |
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| 疾病 |
- 紅血球
- 單核球和顆粒球
- 腫瘤與癌症
- 組織細胞增多症
症狀和體徵
驗血
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| 治療 |
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