Agfdhyk

This page lists enzymes by their classification in the International Union of Biochemistry and Molecular Biology's Enzyme Commission [EC] numbering system. For a list of the EC numbers themselves, see:

• List of EC numbers (EC 1)


• List of EC numbers (EC 2)


• List of EC numbers (EC 3)


• List of EC numbers (EC 4)


• List of EC numbers (EC 5)


• List of EC numbers (EC 6)

Category:Oxidoreductases (EC 1) (Oxidoreductase)

• Dehydrogenase


• Luciferase


• DMSO reductase

Category:EC 1.1 (act on the CH-OH group of donors)

• 
  Category:EC 1.1.1 (with NAD⁺ or NADP⁺ as acceptor)
  
  
  
  • 
    Alcohol dehydrogenase (NAD) EC 1.1.1.1
    
  
  
  • 
    Alcohol dehydrogenase (NADP) EC 1.1.1.2
    
  
  
  • 
    Homoserine dehydrogenase EC 1.1.1.3
    
  
  
  • 
    Aminopropanol oxidoreductase EC 1.1.1.4
    
  
  
  • 
    Diacetyl reductase EC 1.1.1.5
    
  
  
  • 
    Glycerol dehydrogenase EC 1.1.1.6
    
  
  
  • 
    Propanediol-phosphate dehydrogenase EC 1.1.1.7
    
  
  
  • 
    glycerol-3-phosphate dehydrogenase (NAD+) EC 1.1.1.8
    
  
  
  • 
    D-xylulose reductase EC 1.1.1.9
    
  
  
  • 
    L-xylulose reductase EC 1.1.1.10
    
  
  
  • 
    Lactate dehydrogenase EC 1.1.1.27
    
  
  
  • 
    Malate dehydrogenase EC 1.1.1.37
    
  
  
  • 
    Isocitrate dehydrogenase EC 1.1.1.42
    
  
  
  • 
    HMG-CoA reductase EC 1.1.1.88
    
  
  
  
  


• 
  Category:EC 1.1.2 (with a cytochrome as acceptor)


• 
  Category:EC 1.1.3 (with oxygen as acceptor)
  
  
  
  • 
    Glucose oxidase EC 1.1.3.4
    
  
  
  • 
    L-gulonolactone oxidase EC 1.1.3.8
    
  
  
  • 
    Thiamine oxidase EC 1.1.3.23
    
  
  
  • 
    Xanthine oxidase EC 1.1.3.32
    
  
  
  
  


• 
  Category:EC 1.1.4 (with a disulfide as acceptor)


• 
  Category:EC 1.1.5 (with a quinone or similar compound as acceptor)


• 
  Category:EC 1.1.99 (with other acceptors)

Category:EC 1.2 (act on the aldehyde or oxo group of donors)

• 
  Category:EC 1.2.1 (with NAD⁺ or NADP⁺ as acceptor)
  
  
  
  • 
    Acetaldehyde dehydrogenase EC 1.2.1.10
    
  
  
  • 
    Glyceraldehyde 3-phosphate dehydrogenase EC 1.2.1.12
    
  
  
  • 
    Pyruvate dehydrogenase EC 1.2.1.51
    
  
  
  
  


• 
  Category:EC 1.2.4
  
  • 
    Oxoglutarate dehydrogenase EC 1.2.4.2
    
  
  

Category:EC 1.3 (act on the CH-CH group of donors)

• 
  Category:EC 1.3.1 (with NAD⁺ or NADP⁺ as acceptor)
  
  • 
    Biliverdin reductase EC 1.3.1.24
    
  
  


• 
  Category:EC 1.3.2 (with a cytochrome as acceptor)


• 
  Category:EC 1.3.3 (with oxygen as acceptor)
  
  • 
    Protoporphyrinogen oxidase EC 1.3.3.4
    
  
  


• 
  Category:EC 1.3.5 (with a quinone or similar compound as acceptor)


• 
  Category:EC 1.3.7 (with an iron-sulfur protein as acceptor)


• 
  Category:EC 1.3.99 (with other acceptors)

Category:EC 1.4 (act on the CH-NH₂ group of donors)

• 
  Category:EC 1.4.3
  
  • 
    Monoamine oxidase EC 1.4.3.4
    
  
  

Category:EC 1.5 (act on CH-NH group of donors)

• 
  Category:EC 1.5.1 (with NAD⁺ or NADP⁺ as acceptor)
  
  
  
  • 
    Dihydrofolate reductase EC 1.5.1.3
    
  
  
  • 
    Methylenetetrahydrofolate reductase EC 1.5.1.20
    
  
  
  
  


• 
  Category:EC 1.5.3 (with oxygen as acceptor)
  
  
  
  • 
    Sarcosine oxidase EC 1.5.3.1
    
  
  
  • 
    Dihydrobenzophenanthridine oxidase EC 1.5.3.12
    
  
  
  
  


• 
  Category:EC 1.5.4 (with a disulfide as acceptor)


• 
  Category:EC 1.5.5 (with a quinone or similar compound as acceptor)


• 
  Category:EC 1.5.7 (with an iron-sulfur protein as acceptor)


• 
  Category:EC 1.5.8 (with a flavin as acceptor)


• 
  Category:EC 1.5.99 (with other acceptors)

Category:EC 1.6 (act on NADH or NADPH)

• 
  Category:EC 1.6.1 (with NAD⁺ or NADP⁺ as acceptor)


• 
  Category:EC 1.6.2 (with a cytochrome as acceptor)


• 
  Category:EC 1.6.3 (with oxygen as acceptor)


• 
  Category:EC 1.6.4 now Category:EC 1.8.1
  


• 
  Category:EC 1.6.5 (with a quinone or similar compound as acceptor)
  
  • 
    NADH dehydrogenase EC 1.6.5.3
    
  
  


• 
  Category:EC 1.6.6 (with a nitrogenous group as acceptor)


• 
  Category:EC 1.6.7 now Category:EC 1.18.1
  


• 
  Category:EC 1.6.8 now Category:EC 1.5.1
  


• 
  Category:EC 1.6.99 (with other acceptors)

Category:EC 1.7 (act on other nitrogenous compounds as donors)

• 
  Category:EC 1.7.1 (with NAD⁺ or NADP⁺ as acceptor)


• 
  Category:EC 1.7.2 (with a cytochrome as acceptor)


• 
  Category:EC 1.7.3 (with oxygen as acceptor)
  
  • 
    Urate oxidase EC 1.7.3.3
    
  
  


• 
  Category:EC 1.7.7 (with an iron-sulfur protein as acceptor)


• 
  Category:EC 1.7.99 (with other acceptors)
  
  
  
  • 
    Nitrite reductase EC 1.7.99.3
    
  
  
  • 
    Nitrate reductase EC 1.7.99.4
    
  
  
  
  

Category:EC 1.8 (act on a sulfur group of donors)

• 
  Category:EC 1.8.1 (with NAD⁺ or NADP⁺ as acceptor)
  
  
  
  • 
    Glutathione reductase EC 1.8.1.7
    
  
  
  • 
    Thioredoxin reductase EC 1.8.1.9
    
  
  
  
  


• 
  Category:EC 1.8.2 (with a cytochrome as acceptor)


• 
  Category:EC 1.8.3 (with oxygen as acceptor)
  
  • 
    Sulfite oxidase EC 1.8.3.1
    
  
  


• 
  Category:EC 1.8.4 (with a disulfide as acceptor)


• 
  Category:EC 1.8.5 (with a quinone or similar compound as acceptor)


• 
  Category:EC 1.8.6 deleted, included in EC 2.5.1.18
  


• 
  Category:EC 1.8.7 (with an iron-sulfur protein as acceptor)


• 
  Category:EC 1.8.98 (with other, known, acceptors)


• 
  Category:EC 1.8.99 (with other acceptors)

Category:EC 1.9 (act on a heme group of donors)

• 
  Category:EC 1.9.3 (with oxygen as acceptor)
  
  • 
    Cytochrome c oxidase EC 1.9.3.1
    
  
  


• 
  Category:EC 1.9.6 (with a nitrogenous as acceptor)


• 
  Category:EC 1.9.99 transferred, now EC 1.9.98.1
  

Category:EC 1.10 (act on diphenols and related substances as donors)

• 
  Category:EC 1.10.1(with NAD⁺ or NADP⁺ as acceptor)


• 
  Category:EC 1.10.2 (with a cytochrome as acceptor)
  
  • 
    Coenzyme Q - cytochrome c reductase EC 1.10.2.2
    
  
  


• 
  Category:EC 1.10.3 (with oxygen as acceptor)
  
  
  
  • 
    Catechol oxidase EC 1.10.3.1
    
  
  
  • 
    Laccase EC 1.10.3.2
    
  
  
  
  


• 
  Category:EC 1.10.99 (with other acceptors)

Category:EC 1.11 (act on peroxide as an acceptor -- peroxidases)

• 
  Category:EC 1.11.1 (peroxidases)
  
  
  
  • 
    Cytochrome c peroxidase EC 1.11.1.5
    
  
  
  • 
    Catalase EC 1.11.1.6
    
  
  
  • 
    Myeloperoxidase EC 1.11.1.7
    
  
  
  • 
    Thyroid peroxidase EC 1.11.1.8
    
  
  
  • 
    Glutathione peroxidase EC 1.11.1.9
    
  
  
  
  

Category:EC 1.12 (act on hydrogen as a donor)

• 
  Category:EC 1.12.1 (with NAD⁺ or NADP⁺ as acceptor)


• 
  Category:EC 1.12.2 (with a cytochrome as acceptor)


• 
  Category:EC 1.12.5 (with a quinone or similar compound as acceptor)


• 
  Category:EC 1.12.7 (with an iron-sulfur protein as acceptor)


• 
  Category:EC 1.12.98 (with other known acceptors)


• 
  Category:EC 1.12.99 (with other acceptors)

Category:EC 1.13 (act on single donors with incorporation of molecular oxygen)

• 
  Category:EC 1.13.11 (With incorporation of two atoms of oxygen)
  
  • 
    4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27)
  
  


• 
  Category:EC 1.13.12 (With incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases))
  
  
  
  • 
    Renilla-luciferin 2-monooxygenase EC 1.13.12.5
    
  
  
  • 
    Cypridina-luciferin 2-monooxygenase EC 1.13.12.6
    
  
  
  • 
    Firefly luciferase EC 1.13.12.7
    
  
  
  • 
    Watasenia-luciferin 2-monooxygenase EC 1.13.12.8
    
  
  
  • 
    Oplophorus-luciferin 2-monooxygenase EC 1.13.12.13
    
  
  
  
  

Category:EC 1.14 (act on paired donors with incorporation of molecular oxygen)

• Cytochrome P450 oxidase


• 
  Category:Cytochrome P450
  
  
  
  • 
    Aromatase EC 1.14.14.1
    
  
  
  • 
    CYP2D6 EC 1.14.14.1
    
  
  
  • 
    CYP2E1 EC 1.14.14.1
    
  
  
  • 
    CYP3A4 EC 1.14.14.1
    
  
  
  • Cytochrome P450 oxidase
  
  
  
  


• 
  Category:EC 1.14.12
  
  • Nitric oxide dioxygenase
  
  


• 
  Category:EC 1.14.13
  
  • 
    Nitric oxide synthase EC 1.14.13.39
    
  
  


• 
  Category:EC 1.14.14
  
  
  
  • 
    Aromatase EC 1.14.14.1
    
  
  
  • 
    CYP2D6 EC 1.14.14.1
    
  
  
  • 
    CYP2E1 EC 1.14.14.1
    
  
  
  • 
    CYP3A4 EC 1.14.14.1
    
  
  
  
  


• 
  Category:EC 1.14.16
  
  • 
    Phenylalanine hydroxylase EC 1.14.16.1
    
  
  


• 
  Category:EC 1.14.18
  
  • 
    Tyrosinase EC 1.14.18.1
    
  
  

Category:EC 1.15 (act on superoxide radicals as acceptors)

• 
  Category:EC 1.15.1
  
  • 
    Superoxide dismutase EC 1.15.1.1
    
  
  

Category:EC 1.16 (oxidize metal ions)

• 
  Category:EC 1.16.3
  
  • 
    Ceruloplasmin EC 1.16.3.1
    
  
  

Category:EC 1.17 (act on CH or CH₂ groups)

• 
  Category:EC 1.17.1
  
  
  
  • 
    Leucoanthocyanidin reductase EC 1.17.1.3
    
  
  
  • 
    Xanthine dehydrogenase EC 1.17.1.4
    
  
  
  • 
    Nicotinate dehydrogenase EC 1.17.1.5
    
  
  
  • 
    4-hydroxy-tetrahydrodipicolinate reductase EC 1.17.1.8
    
  
  
  
  


• 
  Category:EC 1.17.2
  
  • 
    Nicotinate dehydrogenase (cytochrome) EC 1.17.2.1
    
  
  


• 
  Category:EC 1.17.3
  
  • 
    Xanthine oxidase EC 1.17.3.2
    
  
  


• 
  Category:EC 1.17.4
  
  
  
  • 
    Ribonucleotide reductase EC 1.17.4.1
    
  
  
  • 
    Ribonucleoside-triphosphate reductase EC 1.17.4.2
    
  
  
  • Vitamin K epoxide reductase
  
  
  • 
    Vitamin-K-epoxide reductase (warfarin-sensitive) EC 1.17.4.4
    
  
  
  • 
    Vitamin-K-epoxide reductase (warfarin-insensitive) EC 1.17.4.5
    
  
  
  • RRM1
  
  
  • RRM2
  
  
  • RRM2B
  
  
  
  


• 
  Category:EC 1.17.5
  
  • 
    Caffeine dehydrogenase EC 1.17.5.2
    
  
  


• Category:EC 1.17.7


• Category:EC 1.17.99

Category:EC 1.18 (act on iron-sulfur proteins as donors)

• 
  Category:EC 1.18.6
  
  • 
    Nitrogenase EC 1.18.6.1
    
  
  

Category:EC 1.19 (act on reduced flavodoxin as donor)

• 
  Category:EC 1.19.6
  
  • 
    Nitrogenase (flavodoxin) EC 1.19.6.1
    
  
  

Category:EC 1.20 (act on phosphorus or arsenic as donors)

• Category:EC 1.20.1


• Category:EC 1.20.2


• 
  Category:EC 1.20.4
  
  
  
  • 
    Arsenate reductase (glutaredoxin) EC 1.20.4.1
    
  
  
  • Glutaredoxin
  
  
  
  


• Category:EC 1.20.9


• Category:EC 1.20.99

Category:EC 1.21 (act on X-H and Y-H to form an X-Y bond)

• 
  Category:EC 1.21.1
  
  • 
    Iodotyrosine deiodinase EC 1.21.1.1
    
  
  


• 
  Category:EC 1.21.3
  
  
  
  • 
    Isopenicillin N synthase EC 1.21.3.1
    
  
  
  • 
    Tetrahydrocannabinolic acid synthase EC 1.21.3.7
    
  
  
  
  


• Category:EC 1.21.4


• 
  Category:EC 1.21.99
  
  
  
  • 
    Thyroxine 5-deiodinase EC 1.21.99.3
    
  
  
  • 
    Iodothyronine deiodinase EC 1.21.99.3 and EC 1.21.99.4
    
  
  
  
  

Category:EC 1.97 (other oxidoreductases)

• 
  Category:EC 1.97.1
  
  • 
    Deiodinase EC 1.97.1.10
    
  
  

Category:Transferases (EC 2) (Transferase)

• Glutathione S-transferase

Category:EC 2.1 (transfer one-carbon groups, Methylase)

• 
  Category:EC 2.1.1
  
  
  
  • 
    Catechol-O-methyl transferase EC 2.1.1.6
    
  
  
  • 
    DNA methyltransferase EC 2.1.1.72, EC 2.1.1.113, EC 2.1.1.37
    
  
  
  • 
    Histone methyltransferase EC 2.1.1.43, EC 2.1.1.125
    
  
  
  
  


• 
  Category:EC 2.1.3
  
  
  
  • 
    Aspartate transcarbamoylase EC 2.1.3.2
    
  
  
  • 
    Ornithine transcarbamoylase EC 2.1.3.3
    
  
  
  
  

Category:EC 2.2 (transfer aldehyde or ketone groups)

• 
  Category:EC 2.2.1
  
  
  
  • 
    Transketolase EC 2.2.1.1
    
  
  
  • 
    Transaldolase EC 2.2.1.2
    
  
  
  • 
    Acetolactate synthase EC 2.2.1.6
    
  
  
  • 
    2-Succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase EC 2.2.1.9
    
  
  
  
  

Category:EC 2.3 (acyltransferases)

• 
  Category:EC 2.3.1
  
  
  
  • 
    Aminolevulinic acid synthase EC 2.3.1.37
    
  
  
  • 
    Choline acetyltransferase EC 2.3.1.6
    
  
  
  
  


• 
  Category:EC 2.3.2
  
  
  
  • 
    Factor XIII EC 2.3.2.13
    
  
  
  • 
    Gamma glutamyl transpeptidase EC 2.3.2.2
    
  
  
  • 
    Transglutaminase EC 2.3.2.13
    
  
  
  
  

Category:EC 2.4 (glycosyltransferases)

• 
  Category:EC 2.4.2
  
  • 
    Hypoxanthine-guanine phosphoribosyltransferase EC 2.4.2.8
    
  
  

Category:EC 2.5

• 
  Category:EC 2.5.1
  
  • 
    Thiaminase EC 2.5.1.2
    
  
  

Category:EC 2.5 (transfer alkyl or aryl groups, other than methyl groups)

• • 
    Flavin prenyltransferase EC 2.5.1.129
    

Category:EC 2.6 (transfer nitrogenous groups)

• 
  Category:EC 2.6.1
  
  
  
  • 
    Alanine transaminase EC 2.6.1.2
    
  
  
  • 
    Aspartate transaminase EC 2.6.1.1
    
  
  
  
  

Category:EC 2.7 (transfer phosphorus-containing groups)

• 
  Category:EC 2.7.2
  
  • 
    Butyrate kinase (EC 2.7.2.7)
  
  

Category:EC 2.8 (transfer sulfur-containing groups)

• 
  EC 2.8.1.1: Thiosulfate sulfurtransferase
  


• 
  EC 2.8.1.2: 3-mercaptopyruvate sulfurtransferase
  


• 
  EC 2.8.1.3: Thiosulfate--thiol sulfurtransferase
  


• 
  EC 2.8.1.4: tRNA uracil 4-sulfurtransferase
  


• 
  EC 2.8.1.5: Thiosulfate--dithiol sulfurtransferase
  


• 
  EC 2.8.1.6: Biotin synthase
  


• 
  EC 2.8.1.7: Cysteine desulfurase
  


• 
  EC 2.8.1.8: Lipoyl synthase
  


• 
  EC 2.8.1.9: Molybdenum cofactor sulfurtransferase
  


• 
  EC 2.8.1.10: Thiazole synthase
  


• 
  EC 2.8.1.11: Molybdopterin synthase sulfurtransferase
  


• 
  EC 2.8.1.12: Molybdopterin synthase
  


• 
  EC 2.8.1.13: tRNA-uridine 2-sulfurtransferase
  


• 
  EC 2.8.1.14: tRNA-5-taurinomethyluridine 2-sulfurtransferase
  


• 
  EC 2.8.1.15: tRNA-5-methyluridine(54) 2-sulfurtransferase
  

Category:EC 2.9 (transfer selenium-containing groups)

• 
  EC 2.9.1.1: L-seryl-tRNA(Sec) selenium transferase
  


• 
  EC 2.9.1.2: O-phospho-L-seryl-tRNA(Sec):L-selenocysteinyl-tRNA synthase
  

Category:Hydrolases (EC 3) (Hydrolase)

• Hydrolytic enzyme

Category:EC 3.1 (act on ester bonds)

• Nuclease


• Endonuclease


• Exonuclease


• 
  Category:EC 3.1.1
  
  
  
  • Acid hydrolase
  
  
  • 
    Phospholipase A (EC 3.1.1.4)
  
  
  • 
    Acetylcholinesterase (EC 3.1.1.7)
  
  
  • 
    Cholinesterase (EC 3.1.1.8)
  
  
  • 
    Lipoprotein lipase (EC 3.1.1.34)
  
  
  
  


• 
  Category:EC 3.1.2
  
  • 
    Ubiquitin carboxy-terminal hydrolase L1 (EC 3.1.2.15)
  
  


• 
  Category:EC 3.1.3
  
  
  
  • Phosphatase
  
  
  • 
    Alkaline phosphatase (EC 3.1.3.1)
  
  
  • 
    Fructose bisphosphatase (EC 3.1.3.11)
  
  
  
  


• 
  Category:EC 3.1.4
  
  
  
  • 
    Phospholipase C (EC 3.1.4.3)
  
  
  • 
    CGMP specific phosphodiesterase type 5 (EC 3.1.4.17)
  
  
  • 
    Phospholipase D (EC 3.1.4.50)
  
  
  
  


• 
  Category:EC 3.1.21
  
  
  
  • 
    Restriction enzyme Type 1 (EC 3.1.21.3)
  
  
  • 
    Restriction enzyme Type 2 (EC 3.1.21.4)
  
  
  • 
    Restriction enzyme Type 3 (EC 3.1.21.5)
  
  
  • 
    Restriction enzyme Type 4 (?)
  
  
  • 
    Deoxyribonuclease I (EC 3.1.21.1)
  
  
  
  


• 
  Category:EC 3.1.26
  
  • 
    RNase H (EC 3.1.26.4)
  
  


• 
  Category:EC 3.1.27
  
  • Ribonuclease
  
  

Category:EC 3.2 (act on sugars - glycosylases)

• 
  Category:EC 3.2.1
  
  
  
  • 
    Amylase (EC 3.2.1.1)
  
  
  • 
    Sucrase (EC 3.2.1.10)
  
  
  • 
    Chitinase (EC 3.2.1.14)
  
  
  • 
    Lysozyme (EC 3.2.1.17)
  
  
  • 
    Maltase (EC 3.2.1.20)
  
  
  • 
    Lactase (EC 3.2.1.23)
  
  
  • 
    Beta-galactosidase (EC 3.2.1.23)
  
  
  • 
    Hyaluronidase (EC 3.2.1.35)
  
  
  
  

Category:EC 3.3 (act on ether bonds)

• Category:EC 3.3


• Adenosylmethionine hydrolase


• S-adenosyl-L-homocysteine hydrolase


• Alkenylglycerophosphocholine hydrolase


• Alkenylglycerophosphoethanolamine hydrolase


• Cholesterol-5,6-oxide hydrolase


• Hepoxilin-epoxide hydrolase


• Isochorismatase


• Leukotriene-A4 hydrolase


• Limonene-1,2-epoxide hydrolase


• Microsomal epoxide hydrolase


• Trans-epoxysuccinate hydrolase

Category:EC 3.4 (act on peptide bonds - Peptidase)

• 
  Category:EC 3.4.11
  
  • Alanine aminopeptidase
  
  


• 
  Category:EC 3.4.15
  
  • Angiotensin converting enzyme
  
  


• 
  Category:EC 3.4.21
  
  
  
  • Serine protease
  
  
  • 
    Chymotrypsin (EC 3.4.21.1)
  
  
  • 
    Trypsin (EC 3.4.21.4)
  
  
  • 
    Thrombin (EC 3.4.21.5)
  
  
  • 
    Factor X (EC 3.4.21.6)
  
  
  • 
    Plasmin (EC 3.4.21.7)
  
  
  • 
    Acrosin (EC 3.4.21.10)
  
  
  • 
    Factor VII (EC 3.4.21.21)
  
  
  • 
    Factor IX (EC 3.4.21.22)
  
  
  • 
    Prolyl oligopeptidase (EC 3.4.21.26)
  
  
  • 
    Factor XI (EC 3.4.21.27)
  
  
  • 
    Elastase (EC 3.4.21.37)
  
  
  • 
    Factor XII (EC 3.4.21.38)
  
  
  • 
    Proteinase K (EC 3.4.21.64)
  
  
  • 
    Tissue plasminogen activator (EC 3.4.21.68)
  
  
  • 
    Protein C (EC 3.4.21.69)
  
  
  
  


• 
  Category:EC 3.4.22
  
  • 
    Separase (EC 3.4.22.49)
  
  


• 
  Category:EC 3.4.23
  
  
  
  • 
    Pepsin (EC 3.4.23.1)
  
  
  • 
    Rennet (EC 3.4.23.4)
  
  
  • 
    Renin (EC 3.4.23.15)
  
  
  • 
    Trypsinogen (EC 3.4.23.18) and (20/21/23/24/26)
  
  
  • 
    Plasmepsin (EC 3.4.23.39)
  
  
  
  


• 
  Category:EC 3.4.24
  
  • 
    Matrix metalloproteinase (EC 3.4.24.7)
  
  


• 
  Category:EC 3.4.25
  
  • Metalloendopeptidase
  
  

Category:EC 3.5 (act on carbon-nitrogen bonds, other than peptide bonds)

• 
  Category:EC 3.5.1 (In linear amides)
  
  • 
    Urease (EC 3.5.1.5)
  
  


• 
  Category:EC 3.5.2 (In cyclic amides)
  
  • 
    Beta-lactamase (EC 3.5.2.6)
  
  


• 
  Category:EC 3.5.3 (In linear amidines)
  
  • 
    Arginase (EC 3.5.3.1)
  
  


• 
  Category:EC 3.5.4 (In cyclic amidines)
  
  
  
  • 
    Adenosine deaminase (EC 3.5.4.4)
  
  
  • 
    GTP cyclohydrolase I (EC 3.5.4.16)
  
  
  
  


• 
  Category:EC 3.5.5 (In nitriles)
  
  • 
    Nitrilase (EC 3.5.5.1)
  
  

Category:EC 3.6 (act on acid anhydrides)

• 
  Category:EC 3.6.1
  
  
  
  • Helicase
  
  
  • DnaB helicase
  
  
  • RecQ helicase
  
  
  
  


• 
  Category:EC 3.6.3
  
  
  
  • ATPase
  
  
  • 
    NaKATPase (EC 3.6.3.9)
  
  
  • 
    ATP synthase (EC 3.6.3.14)
  
  
  
  

Category:EC 3.7 (act on carbon-carbon bonds)

• 
  Kynureninase EC 3.7.1.3
  

Category:EC 3.8 (act on halide bonds)

• EC 3.8.1.3 Haloacetate dehalogenase
  

Category:EC 3.9 (act on phosphorus-nitrogen bonds)

• 
  EC 3.9.1.1: Phosphoamidase
  


• 
  EC 3.9.1.2: Protein arginine phosphatase
  


• 
  EC 3.9.1.3: Phosphohistidine phosphatase
  

Category:EC 3.10 (act on sulfur-nitrogen bonds)

• 
  EC 3.10.1.1: N-sulfoglucosamine sulfohydrolase
  


• 
  EC 3.10.1.2: Cyclamate sulfohydrolase
  

Category:EC 3.11 (act on carbon-phosphorus bonds)

• 
  EC 3.11.1.1: Phosphonoacetaldehyde hydrolase
  


• 
  EC 3.11.1.2: Phosphonoacetate hydrolase
  


• 
  EC 3.11.1.3: Phosphonopyruvate hydrolase
  

Category:EC 3.12 (act on sulfur-sulfur bonds)

• 
  EC 3.12.1.1: Trithionate hydrolase
  

Category:EC 3.13 (act on carbon-sulfur bonds)

• 
  EC 3.13.1.1: UDP-sulfoquinovose synthase
  


• 
  EC 3.13.1.3: 2'-hydroxybiphenyl-2-sulfinate desulfinase
  


• 
  EC 3.13.1.4: 3-sulfinopropanoyl-CoA desulfinase
  


• 
  EC 3.13.1.5: Carbon disulfide hydrolase
  


• 
  EC 3.13.1.6: [[[CysO sulfur-carrier protein]-S-L-cysteine hydrolase]]


• 
  EC 3.13.1.7: Carbonyl sulfide hydrolase
  


• 
  EC 3.13.1.8: S-adenosyl-L-methionine hydrolase (adenosine-forming)
  

Category:Lyases (EC 4) (Lyase)

Category:EC 4.1 (carbon-carbon lyases)

• 
  Category:EC 4.1.1
  
  
  
  • 
    Ornithine decarboxylase (EC 4.1.1.17)
  
  
  • 
    Uridine monophosphate synthetase (EC 4.1.1.23)
  
  
  • 
    Aromatic-L-amino-acid decarboxylase (EC 4.1.1.28)
  
  
  • 
    RubisCO (EC 4.1.1.39)
  
  
  
  

• 
  Category:EC 4.1.2
  
  • 
    Fructose-bisphosphate aldolase (EC 4.1.2.13)
  
  

Category:EC 4.2 (carbon-oxygen lyases)

• 
  Category:EC 4.2.1
  
  
  
  • 
    Carbonic anhydrase (EC 4.2.1.1)
  
  
  • 
    Tryptophan synthase (EC 4.2.1.20)
  
  
  
  

Category:EC 4.3 (carbon-nitrogen lyases)

• 
  Category:EC 4.3.1
  
  • 
    Phenylalanine ammonia-lyase (EC 4.3.1.24)
  
  

Category:EC 4.4 (carbon-sulfur lyases)

• 
  Category:EC 4.4.1
  
  
  
  • Cystathionine gamma-lyase
  
  
  • Cystathionine beta-lyase
  
  
  • Leukotriene C4 synthase
  
  
  
  

Category:EC 4.5 (carbon-halide lyases)

• 
  Category:EC 4.5.1
  
  
  
  • Dichloromethane dehalogenase
  
  
  • Halohydrin dehalogenase
  
  
  
  

Category:EC 4.6 (phosphorus-oxygen lyases)

• 
  Category:EC 4.6.1
  
  
  
  • 
    Adenylate cyclase (EC 4.6.1.1)
  
  
  • 
    Guanylate cyclase (EC 4.6.1.2)
  
  
  
  

Category:Isomerases (EC 5) (Isomerase)

Category:EC 5.1 (racemases and epimerases)

• Category:EC 5.1.1


• 
  Amino-acid racemase: Phenylalanine racemase (ATP-hydrolysing)
  


• Serine racemase


• Category:EC 5.1.2


• Mandelate racemase


• Category:EC 5.1.3


• UDP-glucose 4-epimerase


• Category:EC 5.1.99


• Methylmalonyl CoA epimerase

Category:EC 5.2 (cis-trans-isomerases)

• Category:EC 5.2


• 
  FKBP: FKBP1A
  


• FKBP1B


• FKBP2


• FKBP3


• FKBP5


• FKBP6


• FKBP8


• FKBP9


• FKBP10


• FKBP52


• FKBPL


• Cyclophilin


• Parvulin


• Prolyl isomerase


• 2-chloro-4-carboxymethylenebut-2-en-1,4-olide isomerase


• Beta-carotene isomerase


• Farnesol 2-isomerase


• Furylfuramide isomerase


• Linoleate isomerase


• Maleate isomerase


• Maleylacetoacetate isomerase


• Maleylpyruvate isomerase


• Parvulin


• Photoisomerase


• Prolycopene isomerase


• Prolyl isomerase


• Retinal isomerase


• Retinol isomerase


• Zeta-carotene isomerase

Category:EC 5.3 (intramolecular oxidoreductases)

• 
  Category:EC 5.3.3
  
  • 
    Enoyl CoA isomerase (EC 5.3.3.8)
  
  


• 
  Category:EC 5.3.4
  
  • 
    Protein disulfide isomerase (EC 5.3.4.1)
  
  

Category:EC 5.4 (intramolecular transferases -- mutases)

• 
  Category:EC 5.4.2
  
  • 
    Phosphoglucomutase (EC 5.4.2.2)
  
  

Category:EC 5.5 (intramolecular lyases)

Category:EC 5.99 (other isomerases)

• 
  Category:EC 5.99.1
  
  • 
    Topoisomerase (type I: EC 5.99.1.2, type II: EC 5.99.1.3)
  
  

Category:Ligases (EC 6) (Ligase)

Category:EC 6.1 (form carbon-oxygen bonds)

6-carboxytetrahydropterin synthase

• 
  Category:EC 6.1.1
  
  • 
    FARSB (EC 6.1.1.20)
  
  

Category:EC 6.2 (form carbon-sulfur bonds)

• 
  EC 6.2.1.1: Acetate--CoA ligase
  


• 
  EC 6.2.1.2: Medium-chain acyl-CoA ligase
  


• 
  EC 6.2.1.3: Long-chain-fatty-acid--CoA ligase
  


• 
  EC 6.2.1.4: Succinate--CoA ligase (GDP-forming)
  


• 
  EC 6.2.1.5: Succinate--CoA ligase (ADP-forming)
  


• 
  EC 6.2.1.6: Glutarate--CoA ligase
  


• 
  EC 6.2.1.7: Cholate--CoA ligase
  


• 
  EC 6.2.1.8: Oxalate--CoA ligase
  


• 
  EC 6.2.1.9: Malate--CoA ligase
  


• 
  EC 6.2.1.10: Acid--CoA ligase (GDP-forming)
  


• 
  EC 6.2.1.11: Biotin--CoA ligase
  


• 
  EC 6.2.1.12: 4-coumarate--CoA ligase
  


• 
  EC 6.2.1.13: Acetate--CoA ligase (ADP-forming)
  


• 
  EC 6.2.1.14: 6-carboxyhexanoate--CoA ligase
  


• 
  EC 6.2.1.15: Arachidonate--CoA ligase
  


• 
  EC 6.2.1.16: Acetoacetate--CoA ligase
  


• 
  EC 6.2.1.17: Propionate--CoA ligase
  


• 
  EC 6.2.1.18: Citrate--CoA ligase
  


• 
  EC 6.2.1.19: Long-chain-fatty-acid--protein ligase
  


• 
  EC 6.2.1.20: [[Long-chain-fatty-acid--[acyl-carrier-protein] ligase]]


• 
  EC 6.2.1.21: Transferred entry: 6.2.1.30
  


• 
  EC 6.2.1.22: [[[Citrate (pro-3S)-lyase] ligase]]


• 
  EC 6.2.1.23: Dicarboxylate--CoA ligase
  


• 
  EC 6.2.1.24: Phytanate--CoA ligase
  


• 
  EC 6.2.1.25: Benzoate--CoA ligase
  


• 
  EC 6.2.1.26: o-succinylbenzoate--CoA ligase
  


• 
  EC 6.2.1.27: 4-hydroxybenzoate--CoA ligase
  


• 
  EC 6.2.1.28: 3-alpha,7-alpha-dihydroxy-5-beta-cholestanate--CoA ligase
  


• 
  EC 6.2.1.29: Transferred entry: 6.2.1.7
  


• 
  EC 6.2.1.30: Phenylacetate--CoA ligase
  


• 
  EC 6.2.1.31: 2-furoate--CoA ligase
  


• 
  EC 6.2.1.32: Anthranilate--CoA ligase
  


• 
  EC 6.2.1.33: 4-chlorobenzoate--CoA ligase
  


• 
  EC 6.2.1.34: Trans-feruloyl-CoA synthase
  


• 
  EC 6.2.1.35: [[Acetate--[acyl-carrier protein] ligase]]


• 
  EC 6.2.1.36: 3-hydroxypropionyl-CoA synthase
  


• 
  EC 6.2.1.37: 3-hydroxybenzoate--CoA ligase
  


• 
  EC 6.2.1.38: (2,2,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA synthase
  


• 
  EC 6.2.1.39: [[[Butirosin acyl-carrier protein]--L-glutamate ligase]]


• 
  EC 6.2.1.40: 4-hydroxybutyrate--CoA ligase
  


• 
  EC 6.2.1.41: 3-((3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl)propanoate--CoA ligase
  


• 
  EC 6.2.1.42: 3-oxocholest-4-en-26-oate--CoA ligase
  


• 
  EC 6.2.1.43: 2-hydroxy-7-methoxy-5-methyl-1-naphthoate--CoA ligase
  


• 
  EC 6.2.1.44: 3-(methylthio)propionyl--CoA ligase
  


• 
  EC 6.2.1.45: E1 ubiquitin-activating enzyme
  


• 
  EC 6.2.1.46: [[L-allo-isoleucine--holo-[CmaA peptidyl-carrier protein] ligase]]


• 
  EC 6.2.1.47: Medium-chain-fatty-acid--(acyl-carrier-protein) ligase
  


• 
  EC 6.2.1.48: Carnitine--CoA ligase
  


• 
  EC 6.2.1.49: Long-chain fatty acid adenylyltransferase FadD28
  


• 
  EC 6.2.1.50: 4-hydroxybenzoate adenylyltransferase FadD22
  


• 
  EC 6.2.1.51: 4-hydroxyphenylalkanoate adenylyltransferase FadD29
  


• 
  EC 6.2.1.52: L-firefly luciferin--CoA ligase
  


• 
  EC 6.2.1.53: [[L-proline--[L-prolyl-carrier protein] ligase]]


• 
  EC 6.2.1.54: [[D-alanine--[D-alanyl-carrier protein] ligase]]


• 
  EC 6.2.1.55: [[E1 SAMP-activating enzyme]

Category:EC 6.3 (form carbon-nitrogen bonds)

• 
  Glutamine synthetase (EC 6.3.1.2)


• 
  Argininosuccinate synthetase (EC 6.3.4.5)


• 
  CTP synthase (EC 6.3.4.2)

Category:EC 6.4 (form carbon-carbon bonds)

• 
  Pyruvate carboxylase (EC 6.4.1.1)


• 
  Acetyl-CoA carboxylase (EC 6.4.1.2)

Category:EC 6.5 (form phosphoric ester bonds)

DNA ligase (EC 6.5.1.1)

Category:EC 6.6 (form nitrogen-metal bonds)